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Module:
Reverse Impact
Step 1: Select Cancer and Mutation type
Mutation type
All mutation
 
Non-synonymous mutation
Cancer type
Close
ACC: Adrenocortical Carcinoma
BLCA: Bladder Urothelial Carcinoma
BRCA: Breast Invasive Carcinoma
CESC: Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma
CHOL: Cholangiocarcinoma
COAD: Colon Adenocarcinoma
DLBC: Lymphoid Neoplasm Diffuse Large B-cell Lymphoma
ESCA: Esophageal Carcinoma
GBM: Glioblastoma Multiforme
HNSC: Head and Neck Squamous Cell Carcinoma
KICH: Kidney Chromophobe
KIRC: Kidney Renal Clear Cell Carcinoma
KIRP: Kidney Renal Papillary Cell Carcinoma
LAML: Acute Myeloid Leukemia
LGG: Brain Lower Grade Glioma
LIHC: Liver Hepatocellular Carcinoma
LUAD: Lung Adenocarcinoma
LUSC: Lung Squamous Cell Carcinoma
MESO: Mesothelioma
OV: Ovarian Serous Cystadenocarcinoma
PAAD: Pancreatic Adenocarcinoma
PCPG: Pheochromocytoma and Paraganglioma
PRAD: Prostate Adenocarcinoma
READ: Rectum Adenocarcinoma
SARC: Sarcoma
SKCM: Skin Cutaneous Melanoma
STAD: Stomach Adenocarcinoma
TGCT: Testicular Germ Cell Tumors
THCA: Thyroid Carcinoma
THYM: Thymoma
UCEC: Uterine Corpus Endometrial Carcinoma
UCS: Uterine Carcinosarcoma
UVM: Uveal Melanoma
ACC
BLCA
BRCA
CESC
CHOL
COAD
DLBC
ESCA
GBM
HNSC
KICH
KIRC
KIRP
LAML
LGG
LIHC
LUAD
LUSC
MESO
OV
PAAD
PCPG
PRAD
READ
SARC
SKCM
STAD
TGCT
THCA
THYM
UCEC
UCS
UVM
Step 2: Input Genes
OR
Upload File
Select ...
OR
Cancer panel gene lists
(
runtime: ~30 secs per cancer
)
Foundation One
(336 genes)
ThermoFisher
(409 genes)
Step 3: Advanced Options
FDR <
AND
OR
Absolute Fold Change
Optional selection(s)
Cross-Cancer Comparison
(
runtime: ~30sec for 2 cancers
)
Hierarchical clustering and heatmap
(
Number of input genes > 1;
runtime: ~30sec per cancer
)