Welcome to the CoMutDB database !


Welcome to the CoMutDB database. Somatic mutations are one of the most important factors in tumorigenesis and are the focus of most cancer-sequencing efforts. The co-occurrence of multiple mutations in one tumor has gained increasing attention as a means of identifying cooperating mutations or pathways that contribute to cancer. Using multi-omics, phenotypical, and clinical data from 29,559 cancer subjects and 1747 cancer cell lines covering 78 distinct cancer types, we show that co-mutations are associated with prognosis, drug sensitivity, and disparities in sex, age, and race.

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  • Release 1.0 (2020.12.16).
  • Release 2.0 (2022.2.01).
  • Release 2.1 (2022.7.31).