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Differential expression, survival analysis based on mutation status of one or more genes; cross cancer comparison |
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Search for what genes' mutation status can cause target gene(s) to dysregulate. |
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Compare mutation burden between two set of samples determined by a set of genes' mutation status
Co-Mutation: Perform hierarchical cluster between samples of multiple cancer based on mutation status.
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Search for Mutations by gene or genomic locations |
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Subjects are dichotomized based on a quantile of a set of genes' expression, and compared for survival.
Lasso or elastic net based proportinal hazards model is also available for feature selection purpose. Gene Expression Composite Score can be computed.
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Differential expression and mutational burden analysis between subjects with good and poor survival.
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Gene expression based mutational signature inference |