Choose the functionalities from below:
Module Explanation
Differential expression, survival analysis based on mutation status of one or more genes; cross cancer comparison
Search for what genes' mutation status can cause target gene(s) to dysregulate.
Compare mutation burden between two set of samples determined by a set of genes' mutation status
Co-Mutation: Perform hierarchical cluster between samples of multiple cancer based on mutation status.
Search for Mutations by gene or genomic locations
Subjects are dichotomized based on a quantile of a set of genes' expression, and compared for survival. Lasso or elastic net based proportinal hazards model is also available for feature selection purpose. Gene Expression Composite Score can be computed.
Differential expression and mutational burden analysis between subjects with good and poor survival.
Gene expression based mutational signature inference