Cancer List:

None Acute Lymphoblastic Leukemia - TARGET; US Acute Myeloid Leukemia - TARGET; US Bladder Cancer - CN Bladder Urothelial Cancer - TCGA; US Soft Tissue cancer - Ewing sarcoma - FR Bone Cancer - UK B-Cell Prolymphocytic Leukemia - FR Breast ER+ and HER2- Cancer - EU/UK Breast Cancer - FR Breast Cancer - Very young women -KR Breast Triple Negative/Lobular Cancer - UK Breast Cancer - TCGA; US Biliary Tract Cancer - JP Biliary Tract Cancer - SG Cervical Squamous Cell Carcinoma - TCGA; US Chronic Lymphocytic Leukemia - ES Chronic Myeloid Disorders - UK Colon Adenocarcinoma - TCGA; US Colorectal Cancer - CN Lymphoid Neoplasm Diffuse Large B-cell Lymphoma - TCGA; US Early Onset Prostate Cancer - DE Esophageal Adenocarcinoma - UK Esophageal Cancer - CN Gastric Cancer - CN Gastric Cancer - JP Brain Glioblastoma Multiforme - TCGA; US Head and Neck Squamous Cell Carcinoma - TCGA; US Kidney Chromophobe - TCGA; US Kidney Renal Clear Cell Carcinoma - TCGA; US Kidney Renal Papillary Cell Carcinoma - TCGA; US Leukemia - CN Acute Myeloid Leukemia - KR Acute Myeloid Leukemia - TCGA; US Brain Lower Grade Glioma - TCGA; US Benign Liver Tumour - FR Liver Cancer - CN Liver Cancer - FR Liver Hepatocellular carcinoma - TCGA; US Liver Cancer - Hepatocellular macronodules -FR Liver Cancer - NCC; JP Liver Cancer - RIKEN; JP Soft tissue cancer - Leiomyosarcoma - FR Lung Adenocarcinoma - TCGA; US Lung Cancer - CN Lung Cancer - KR Lung Squamous Cell Carcinoma - TCGA; US Malignant Lymphoma - DE Skin Cancer - AU Nasopharyngeal cancer - CN Neuroblastoma - TARGET; US Blood Cancer - T-cell and NK-cell lymphoma - SG Oral Cancer - IN Ovarian Cancer - AU Ovarian Serous Cystadenocarcinoma - TCGA; US Pancreatic Cancer - TCGA; US Pancreatic Cancer - AU Pancreatic Cancer - CA Pancreatic Cancer Endocrine neoplasms - AU Pancreatic Endocrine Neoplasms - IT Pediatric Brain Cancer - DE Pediatric Brain Tumor - Multiple subtypes - US Pediatric Medulloblastoma - CA Prostate Adenocarcinoma - CA Prostate Cancer - CN Prostate Cancer - Adenocarcinoma - FR Prostate Adenocarcinoma - UK Prostate Adenocarcinoma - TCGA; US Rectum Adenocarcinoma - TCGA; US Renal Cancer - CN Renal Cell Cancer - EU/FR Rhabdoid Tumors - TARGET; US Sarcoma - TCGA; US Skin Adenocarcinoma - BR Skin Cutaneous melanoma - TCGA; US Gastric Adenocarcinoma - TCGA; US Thyroid Cancer - CN Thyroid Cancer - SA Head and Neck Thyroid Carcinoma - TCGA; US Uterine Corpus Endometrial Carcinoma- TCGA; US Uterine Cancer - Carcinosarcoma - FR Wilms Tumor - TARGET; US

Selected cancer Types:

• Acute Lymphoblastic Leukemia - TARGET; US (ALL-US)×
• Acute Myeloid Leukemia - TARGET; US (AML-US)×
• Bladder Cancer - CN (BLCA-CN)×
• Bladder Urothelial Cancer - TCGA; US (BLCA-US)×
• Soft Tissue cancer - Ewing sarcoma - FR (BOCA-FR)×
• Bone Cancer - UK (BOCA-UK)×
• B-Cell Prolymphocytic Leukemia - FR (BPLL-FR)×
• Breast ER+ and HER2- Cancer - EU/UK (BRCA-EU)×
• Breast Cancer - FR (BRCA-FR)×
• Breast Cancer - Very young women -KR (BRCA-KR)×
• Breast Triple Negative/Lobular Cancer - UK (BRCA-UK)×
• Breast Cancer - TCGA; US (BRCA-US)×
• Biliary Tract Cancer - JP (BTCA-JP)×
• Biliary Tract Cancer - SG (BTCA-SG)×
• Cervical Squamous Cell Carcinoma - TCGA; US (CESC-US)×
• Chronic Lymphocytic Leukemia - ES (CLLE-ES)×
• Chronic Myeloid Disorders - UK (CMDI-UK)×
• Colon Adenocarcinoma - TCGA; US (COAD-US)×
• Colorectal Cancer - CN (COCA-CN)×
• Lymphoid Neoplasm Diffuse Large B-cell Lymphoma - TCGA; US (DLBC-US)×
• Early Onset Prostate Cancer - DE (EOPC-DE)×
• Esophageal Adenocarcinoma - UK (ESAD-UK)×
• Esophageal Cancer - CN (ESCA-CN)×
• Gastric Cancer - CN (GACA-CN)×
• Gastric Cancer - JP (GACA-JP)×
• Brain Glioblastoma Multiforme - TCGA; US (GBM-US)×
• Head and Neck Squamous Cell Carcinoma - TCGA; US (HNSC-US)×
• Kidney Chromophobe - TCGA; US (KICH-US)×
• Kidney Renal Clear Cell Carcinoma - TCGA; US (KIRC-US)×
• Kidney Renal Papillary Cell Carcinoma - TCGA; US (KIRP-US)×
• Leukemia - CN (LAML-CN)×
• Acute Myeloid Leukemia - KR (LAML-KR)×
• Acute Myeloid Leukemia - TCGA; US (LAML-US)×
• Brain Lower Grade Glioma - TCGA; US (LGG-US)×
• Benign Liver Tumour - FR (LIAD-FR)×
• Liver Cancer - CN (LICA-CN)×
• Liver Cancer - FR (LICA-FR)×
• Liver Hepatocellular carcinoma - TCGA; US (LIHC-US)×
• Liver Cancer - Hepatocellular macronodules -FR (LIHM-FR)×
• Liver Cancer - NCC; JP (LINC-JP)×
• Liver Cancer - RIKEN; JP (LIRI-JP)×
• Soft tissue cancer - Leiomyosarcoma - FR (LMS-FR)×
• Lung Adenocarcinoma - TCGA; US (LUAD-US)×
• Lung Cancer - CN (LUSC-CN)×
• Lung Cancer - KR (LUSC-KR)×
• Lung Squamous Cell Carcinoma - TCGA; US (LUSC-US)×
• Malignant Lymphoma - DE (MALY-DE)×
• Skin Cancer - AU (MELA-AU)×
• Nasopharyngeal cancer - CN (NACA-CN)×
• Neuroblastoma - TARGET; US (NBL-US)×
• Blood Cancer - T-cell and NK-cell lymphoma - SG (NKTL-SG)×
• Oral Cancer - IN (ORCA-IN)×
• Ovarian Cancer - AU (OV-AU)×
• Ovarian Serous Cystadenocarcinoma - TCGA; US (OV-US)×
• Pancreatic Cancer - TCGA; US (PAAD-US)×
• Pancreatic Cancer - AU (PACA-AU)×
• Pancreatic Cancer - CA (PACA-CA)×
• Pancreatic Cancer Endocrine neoplasms - AU (PAEN-AU)×
• Pancreatic Endocrine Neoplasms - IT (PAEN-IT)×
• Pediatric Brain Cancer - DE (PBCA-DE)×
• Pediatric Brain Tumor - Multiple subtypes - US (PBCA-US)×
• Pediatric Medulloblastoma - CA (PEME-CA)×
• Prostate Adenocarcinoma - CA (PRAD-CA)×
• Prostate Cancer - CN (PRAD-CN)×
• Prostate Cancer - Adenocarcinoma - FR (PRAD-FR)×
• Prostate Adenocarcinoma - UK (PRAD-UK)×
• Prostate Adenocarcinoma - TCGA; US (PRAD-US)×
• Rectum Adenocarcinoma - TCGA; US (READ-US)×
• Renal Cancer - CN (RECA-CN)×
• Renal Cell Cancer - EU/FR (RECA-EU)×
• Rhabdoid Tumors - TARGET; US (RT-US)×
• Sarcoma - TCGA; US (SARC-US)×
• Skin Adenocarcinoma - BR (SKCA-BR)×
• Skin Cutaneous melanoma - TCGA; US (SKCM-US)×
• Gastric Adenocarcinoma - TCGA; US (STAD-US)×
• Thyroid Cancer - CN (THCA-CN)×
• Thyroid Cancer - SA (THCA-SA)×
• Head and Neck Thyroid Carcinoma - TCGA; US (THCA-US)×
• Uterine Corpus Endometrial Carcinoma- TCGA; US (UCEC-US)×
• Uterine Cancer - Carcinosarcoma - FR (UTCA-FR)×
• Wilms Tumor - TARGET; US (WT-US)×

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Survival:

 Yes     

Phenotype:

 Age       Gender     

Single Mutation Frequency:

 Yes     

Mutation Type:

 silent       nonsilent       all

Co-mutation logic:

 And       Or       Synergy

Co-mutation gene limit:

 2     3     4   

Co-mutation significance

 Yes